Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model

Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model

Abstract We investigated the effects of anti-CD80/86 antibodies in a murine high-risk corneal transplantation rejection model. A mixed lymphocyte reaction (MLR) assay was conducted with anti-CD80/86 antibodies. Inflammatory cytokine levels in the culture supernatant were measured using an enzyme-lin...

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Bibliographic Details
Main Authors: Jun Zhu, Takenori Inomata, Masahiro Nakamura, Keiichi Fujimoto, Yasutsugu Akasaki, Kenta Fujio, Ai Yanagawa, Koichiro Uchida, Jaemyoung Sung, Naoko Negishi, Ken Nagino, Yuichi Okumura, Maria Miura, Hurramhon Shokirova, Mizu Kuwahara, Kunihiko Hirosawa, Akie Midorikawa-Inomata, Atsuko Eguchi, Tianxiang Huang, Hideo Yagita, Sonoko Habu, Ko Okumura, Akira Murakami
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08949-9

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https://doi.org/10.1038/s41598-022-08949-9

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