The tryptophan catabolite or kynurenine pathway in major depressive and bipolar disorder: A systematic review and meta-analysis

Background: There is now evidence that affective disorders including major depressive disorder (MDD) and bipolar disorder (BD) are mediated by immune-inflammatory and nitro-oxidative pathways. Activation of these pathways may be associated with activation of the tryptophan catabolite (TRYCAT) pathwa...

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Main Authors: Abbas F. Almulla, Yanin Thipakorn, Asara Vasupanrajit, Ali Abbas Abo Algon, Chavit Tunvirachaisakul, Ashwan Abdulzahra Hashim Aljanabi, Gregory Oxenkrug, Hussein K. Al-Hakeim, Michael Maes
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354622001272