Mycolactone: A Broad Spectrum Multitarget Antiviral Active in the Picomolar Range for COVID-19 Prevention and Cure

Mycolactone: A Broad Spectrum Multitarget Antiviral Active in the Picomolar Range for COVID-19 Prevention and Cure

We have previously shown computationally that Mycolactone (MLN), a toxin produced by <i>Mycobacterium ulcerans,</i> strongly binds to Munc18b and other proteins, presumably blocking degranulation and exocytosis of blood platelets and mast cells. We investigated the effect of MLN on endoc...

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Bibliographic Details
Main Authors: Seth Osei Asiedu, Yash Gupta, Vlad Nicolaescu, Haley Gula, Thomas R. Caulfield, Ravi Durvasula, Prakasha Kempaiah, Samuel K. Kwofie, Michael D. Wilson
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
COVID-19
<i>Mycobacterium ulcerans</i>
mycolactone
SARS-CoV-2
viral cell entry and exit
treatment
Online Access:https://www.mdpi.com/1422-0067/24/8/7151

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https://www.mdpi.com/1422-0067/24/8/7151

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