Physcion inhibition of CYP2C9, 2D6 and 3A4 in human liver microsomes

AbstractContext The effect of the active ingredients in traditional Chinese medicines on the activity of cytochrome P450 enzymes (CYP450s) is a critical factor that should be considered in TCM prescriptions. Physcion, the major active ingredient of Rheum spp. (Polygonaceae), possesses wide pharmacol...

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Bibliographic Details
Main Authors: Lu Liu, Sen Sun, Xiaohua Li
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Pharmaceutical Biology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2024.2314089