Indole-3-Propionic Acid, a Gut-Derived Tryptophan Metabolite, Associates with Hepatic Fibrosis

Indole-3-Propionic Acid, a Gut-Derived Tryptophan Metabolite, Associates with Hepatic Fibrosis

Background and Aims: Gut microbiota-derived metabolites play a vital role in maintenance of human health and progression of disorders, including obesity and type 2 diabetes (T2D). Indole-3-propionic acid (IPA), a gut-derived tryptophan metabolite, has been recently shown to be lower in individuals w...

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Bibliographic Details
Main Authors: Ratika Sehgal, Mariana Ilha, Maija Vaittinen, Dorota Kaminska, Ville Männistö, Vesa Kärjä, Marjo Tuomainen, Kati Hanhineva, Stefano Romeo, Päivi Pajukanta, Jussi Pihlajamäki, Vanessa D. de Mello
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Nutrients
Subjects:
indole-3-propionic acid
non-alcoholic fatty liver disease
hepatic fibrosis
hepatic stellate cells
gut microbiota
Online Access:https://www.mdpi.com/2072-6643/13/10/3509

Internet

https://www.mdpi.com/2072-6643/13/10/3509

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