Evaluation of Indolocarbazoles from <i>Streptomyces sanyensis</i> as a Novel Source of Therapeutic Agents against the Brain-Eating Amoeba <i>Naegleria fowleri</i>

Evaluation of Indolocarbazoles from <i>Streptomyces sanyensis</i> as a Novel Source of Therapeutic Agents against the Brain-Eating Amoeba <i>Naegleria fowleri</i>

<i>Naegleria fowleri</i> is an opportunistic pathogenic free-living amoeba which is able to rapidly colonize the central nervous system (CNS) and causes a lethal infection known as primary amoebic meningoencephalitis (PAM). Furthermore, more than 98% of the known cases of PAM are fatal a...

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Bibliographic Details
Main Authors: Aitor Rizo-Liendo, Ines Sifaoui, Luis Cartuche, Iñigo Arberas-Jiménez, María Reyes-Batlle, José J. Fernández, José E. Piñero, Ana R. Díaz-Marrero, Jacob Lorenzo-Morales
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Microorganisms
Subjects:
indolocarbazoles
staurosporine
<i>Naegleria fowleri</i>
brain
amoeba
PAM
Online Access:https://www.mdpi.com/2076-2607/8/5/789

Internet

https://www.mdpi.com/2076-2607/8/5/789

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