Testosterone suppression combined with high dose estrogen as potential treatment of SARS-CoV-2. A mini review

Compared to females, males experience severe acute respiratory syndrome due to COVID-19 (SARS-CoV-2) more often, and also die more frequently from COVID-19. Testosterone has inhibitory and estrogens have favorable effects on the immune system. Both ACE2 and TMPRSS2 are specific host-cellular protein...

Full description

Bibliographic Details
Main Authors: Herjan J.T. Coelingh Bennink, Jan F.M. Egberts, Frans M.J. Debruyne
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022036647