Exploring molecular docking with E-pharmacophore and QSAR models to predict potent inhibitors of 14-α-demethylase protease from Moringa spp
Chagas disease is a neglected tropical disease (NTD) caused by Trypanosoma cruzi, this protozoan is transmitted by kissing bug. Two nitroheterocyclic drugs available for the treatment of chagas disease are not only resistance but also parade toxicity effect. Therefore, this study investigates the in...
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Format: | Article |
Language: | English |
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Elsevier
2022-09-01
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Series: | Pharmacological Research - Modern Chinese Medicine |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2667142522001075 |