Genome-wide DNA methylation profiling in chronic lymphocytic leukaemia

Genome-wide DNA methylation profiling in chronic lymphocytic leukaemia

Background: DNA methylation aberrations are widespread among the malignant B lymphocytes of patients with chronic lymphocytic leukaemia (CLL), suggesting that DNA methylation might contribute to the pathogenesis of CLL.Aim: We aimed to explore the differentially methylated positions (DMPs) associate...

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Bibliographic Details
Main Authors: Qiuyi Zhang, Ying Gao, Shuchun Lin, Lynn R. Goldin, Yonghong Wang, Holly Stevenson, Daniel C. Edelman, Keith Killian, Gerald Marti, Paul S. Meltzer, Song Xiang, Neil E. Caporaso
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
DNA methyaltion
chronic lymphocytic leukaemia (CLL)
illumina 450 K beadchip methylation array
CD19+ B cells
differentially methylated and expressed genes (DMEGs)
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1056043/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.1056043/full

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