Co-introduction of plasmids harbouring the carbapenemase genes, bla NDM-1 and bla OXA-232, increases fitness and virulence of bacterial host

Co-introduction of plasmids harbouring the carbapenemase genes, bla NDM-1 and bla OXA-232, increases fitness and virulence of bacterial host

Abstract Background Bacterial isolates with multiple plasmids harbouring different carbapenemase genes have emerged and been identified repeatedly, despite a general notion that plasmids confer fitness cost in bacterial host. In this study, we investigated the effects of plasmids with carbapenemase...

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Bibliographic Details
Main Authors: Haejeong Lee, Juyoun Shin, Yeun-Jun Chung, Myungseo Park, Kyeong Jin Kang, Jin Yang Baek, Dongwoo Shin, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song, Kwan Soo Ko
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Biomedical Science
Subjects:
Carbapenemase
NDM-1
OXA-232
Plasmid
Plasmid paradox
Online Access:https://doi.org/10.1186/s12929-019-0603-0

Internet

https://doi.org/10.1186/s12929-019-0603-0

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