Simvastatin and Muscle: Zebrafish and Chicken Show that the Benefits are not Worth the Damage

Simvastatin is one of the most common medicines prescribed to treat human hypercholesterolemia. Simvastatin acts through the inhibition of cholesterol synthesis. Unfortunately, simvastatin causes unwanted side effects on muscles, such as soreness, tiredness, or weakness. Therefore, to understand the...

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Bibliographic Details
Main Authors: Laise M. Campos, Livia Guapyassu, Cyro Gomes, Victor Midlej, Marlene Benchimol, Claudia Mermelstein, Manoel Luis Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.778901/full