Efficacy and safety of piperacillin–tazobactam compared with meropenem in treating complicated urinary tract infections including acute pyelonephritis due to extended-spectrum β-lactamase-producing Enterobacteriaceae

IntroductionExtended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae pose a huge threat to human health, especially in the context of complicated urinary tract infections (cUTIs). Carbapenems and piperacillin–tazobactam (PTZ) are two antimicrobial agents commonly used to treat cUTIs.Methods...

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Main Authors: Wei Zhang, Chun-Yu Yan, Shu-Rui Li, Ting-Ting Fan, Shan-Shan Cao, Bin Cui, Meng-Ying Li, Bo-Yuan Fan, Bo Ji, Li Wang, Fei Cui, Jia Cui, Lei Wang, Yue Guan, Jing-Wen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1093842/full