Neuropilin‐1 (NRP1) expression distinguishes self‐reactive helper T cells in systemic autoimmune disease

Neuropilin‐1 (NRP1) expression distinguishes self‐reactive helper T cells in systemic autoimmune disease

Abstract Pathogenic T helper cells (Th cells) that respond to self‐antigen cannot be easily distinguished from beneficial Th cells. These cells can generate systemic autoimmune disease in response to widely expressed self‐antigens. In this study, we have identified neuropilin‐1 (NRP1) as a cell surf...

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Bibliographic Details
Main Authors: Ben JE Raveney, Yosif El‐Darawish, Wakiro Sato, Yoshiyuki Arinuma, Kunihiro Yamaoka, Shohei Hori, Takashi Yamamura, Shinji Oki
Format: Article
Language:English
Published: Springer Nature 2022-09-01
Series:EMBO Molecular Medicine
Subjects:
neuropilin‐1
NR4A2
self‐reactive T helper cells
SLE
systemic autoimmune disease
Online Access:https://doi.org/10.15252/emmm.202215864

Internet

https://doi.org/10.15252/emmm.202215864

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