Impact of Placental SLC2A3 Deficiency during the First-Half of Gestation

Impact of Placental SLC2A3 Deficiency during the First-Half of Gestation

In the ruminant placenta, glucose uptake and transfer are mediated by facilitative glucose transporters SLC2A1 (GLUT1) and SLC2A3 (GLUT3). SLC2A1 is located on the basolateral trophoblast membrane, whereas SLC2A3 is located solely on the maternal-facing, apical trophoblast membrane. While SLC2A3 is...

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Bibliographic Details
Main Authors: Cameron S. Lynch, Victoria C. Kennedy, Amelia R. Tanner, Asghar Ali, Quinton A. Winger, Paul J. Rozance, Russell V. Anthony
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
placenta
glucose uptake
SLC2A3
SLC2A1
insulin
glucagon
Online Access:https://www.mdpi.com/1422-0067/23/20/12530

Internet

https://www.mdpi.com/1422-0067/23/20/12530

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