Type I Interferon and the Spectrum of Susceptibility to Viral Infection and Autoimmune Disease: A Shared Genomic Signature

Type I Interferon and the Spectrum of Susceptibility to Viral Infection and Autoimmune Disease: A Shared Genomic Signature

Type I interferons (IFN-I) and their cognate receptor, the IFNAR1/2 heterodimer, are critical components of the innate immune system in humans. They have been widely explored in the context of viral infection and autoimmune disease where they play key roles in protection against infection or shaping...

Full description

Bibliographic Details
Main Authors: Jamie A. Sugrue, Nollaig M. Bourke, Cliona O’Farrelly
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
infection
autoimmunity
viral resistance
genetics
sexual dimorphism
type I interferons
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.757249/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.757249/full

Similar Items