Approaching the secrets of N-glycosylation in Aspergillus fumigatus: characterization of the AfOch1 protein.

The mannosyltransferase Och1 is the key enzyme for synthesis of elaborated protein N-glycans in yeast. In filamentous fungi genes implicated in outer chain formation are present, but their function is unclear. In this study we have analyzed the Och1 protein of Aspergillus fumigatus. We provide first...

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Bibliographic Details
Main Authors: Andrea Kotz, Johannes Wagener, Jakob Engel, Françoise H Routier, Bernd Echtenacher, Ilse Jacobsen, Jürgen Heesemann, Frank Ebel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3012087?pdf=render