Relationship of microsatellite instability to mismatch repair deficiency in malignant tumors of dogs

Relationship of microsatellite instability to mismatch repair deficiency in malignant tumors of dogs

Abstract Background Microsatellite instability (MSI) is a type of genomic instability caused by mismatch repair deficiency (dMMR) in tumors. Studies on dMMR/MSI are limited, and the relationship between dMMR and MSI is unknown in tumors of dogs. Objectives We aimed to identify the frequency of dMMR/...

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Bibliographic Details
Main Authors: Sakuya Inanaga, Masaya Igase, Yusuke Sakai, Kenji Hagimori, Hiroshi Sunahara, Hiro Horikirizono, Kazuhito Itamoto, Kenji Baba, Yoshiharu Ohsato, Takuya Mizuno
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Journal of Veterinary Internal Medicine
Subjects:
dogs
genomic instability
loss of heterozygosity
oral malignant melanoma
Online Access:https://doi.org/10.1111/jvim.16454

Internet

https://doi.org/10.1111/jvim.16454

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