[Gly14]-Humanin ameliorates high glucose-induced endothelial senescence via SIRT6

[Gly14]-Humanin ameliorates high glucose-induced endothelial senescence via SIRT6

Abstract High glucose (HG) induced endothelial senescence is related to endothelial dysfunction and cardiovascular complications in diabetic patients. Humanin, a member of mitochondrial derived peptides (MDPs), is thought to contribute to aging-related cardiovascular protection. The goal of the stud...

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Bibliographic Details
Main Authors: Muqin Li, Zhihua Liu, Xueqin Cao, Wenjin Xiao, Shurong Wang, Chengyuan Zhao, Ying Zhao, Ying Xie
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Humanin
Senescence
SIRT6
Reactive oxygen species
Endothelial cells
Online Access:https://doi.org/10.1038/s41598-024-81878-x

Internet

https://doi.org/10.1038/s41598-024-81878-x

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