PKCa Agonists Enhance the Protective Effect of Hyaluronic Acid on Nitric Oxide-Induced Apoptosis of Articular Chondrocytes in Vitro

PKCa Agonists Enhance the Protective Effect of Hyaluronic Acid on Nitric Oxide-Induced Apoptosis of Articular Chondrocytes in Vitro

Objective(s): Protein kinase C (PKCα) is involved in modulating articular chondrocytes apoptosis induced by nitric oxide (NO). Hyaluronic acid (HA) inhibits nitric oxide-induced apoptosis of articular chondrocytes by protecting PKCα, but the mechanism remains unclear. The present study was performe...

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Bibliographic Details
Main Authors: Jian-lin Zhou, Hong song Fang, Hao Peng, Qiong jie Hu, Shi qing Liu, Jiang hua Ming, Bo Qiu
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2013-12-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Apoptosis Nitric Oxide PKC-α PMA
Online Access:http://ijbms.mums.ac.ir/pdf_1988_a7fcef3289d7f761a622d581654cb623.html

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http://ijbms.mums.ac.ir/pdf_1988_a7fcef3289d7f761a622d581654cb623.html

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