Preparation and structure characterization of a natural acetylated fructooligosaccharide from Polygonatum sibiricum and its alleviative effect on colitis by inhibiting NLRP3 pathway

Preparation and structure characterization of a natural acetylated fructooligosaccharide from Polygonatum sibiricum and its alleviative effect on colitis by inhibiting NLRP3 pathway

This study aimed to isolate oligosaccharides from P. sibiricum, analyze its structure, and elucidate the pharmacological mechanism for colitis improvement. First, a homogeneous oligosaccharide PSO-A was isolated and its structure was characterized. Then, the colitis model was induced with 3 % dextra...

Full description

Bibliographic Details
Main Authors: Shengchen Ding, Jun Chen, Guangming Chen, Weiyi Tian, Junping Zheng, Haiming Hu, Lu Cao, Xiaowei Yao, Baifei Hu, Hongtao Liu
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Journal of Functional Foods
Subjects:
Polygonatum sibiricum
Oligosaccharide
Characterization
Intestinal inflammation
Colitis
Inflammasome
Online Access:http://www.sciencedirect.com/science/article/pii/S175646462400029X

Internet

http://www.sciencedirect.com/science/article/pii/S175646462400029X

Similar Items