Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?

Abstract Astrocytic dysfunction contributes to the molecular pathogenesis of major depressive disorder (MDD). However, the astrocytic subtype that mainly contributes to MDD etiology and whether dysregulated autophagy in astrocytes is associated with MDD remain unknown. Using a single-nucleus RNA seq...

Full description

Bibliographic Details
Main Authors: Shen He, Yue Shi, Jinmei Ye, Jiahui Yin, Yufang Yang, Dan Liu, Ting Shen, Duan Zeng, Min Zhang, Siyuan Li, Feikang Xu, Yiyun Cai, Faming Zhao, Huafang Li, Daihui Peng
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02665-2

Internet

https://doi.org/10.1038/s41398-023-02665-2

Similar Items