Multiple Roles of Ret Signalling During Enteric Neurogenesis

Multiple Roles of Ret Signalling During Enteric Neurogenesis

The majority of the enteric nervous system is formed by vagal neural crest cells which enter the foregut and migrate rostrocaudally to colonise the entire length of the gastrointestinal tract. Absence of enteric ganglia from the distal colon are the hallmark of Hirschsprung disease, a congenital dis...

Full description

Bibliographic Details
Main Authors: Dipa Natarajan, Conor McCann, Justine Dattani, Vassilis Pachnis, Nikhil Thapar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
enteric nervous system
neural crest cells
Hirschsprung disease
colonic aganglionosis
normoganglionic gut
ENS progenitor cells
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.832317/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.832317/full

Similar Items