Jianpi Huayu Decoction enhances the effect of sorafenib and alleviates adverse events in hepatocellular carcinoma by remodeling the gut microbiota

Background: There is an urgent need for effective treatment for advanced hepatocellular carcinoma (HCC). Sorafenib, a multi-kinase inhibitor, is the first-line treatment for advanced HCC, which has a modest efficacy due to severe adverse effects (AEs), acquired resistance, and others. Jianpi Huayu D...

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Bibliographic Details
Main Authors: Xue Deng, Yingjie Xie, Yantong Lu, Xueyan Li, Xuan Guo, Xuhui Huang, Xiaohe Lan, Juze Lin, Wei Tan, Changjun Wang
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667142522000185