Fast pairwise structural RNA alignments by pruning of the dynamical programming matrix.

It has become clear that noncoding RNAs (ncRNA) play important roles in cells, and emerging studies indicate that there might be a large number of unknown ncRNAs in mammalian genomes. There exist computational methods that can be used to search for ncRNAs by comparing sequences from different genome...

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Bibliographic Details
Main Authors: Jakob H Havgaard, Elfar Torarinsson, Jan Gorodkin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2014794?pdf=render