Remodelling of the Mitochondrial Bioenergetic Pathways in Human Cultured Fibroblasts with Carbohydrates

Mitochondrial oxidative phosphorylation defects underlie many neurological and neuromuscular diseases. Patients’ primary dermal fibroblasts are one of the most commonly used in vitro models to study mitochondrial pathologies. However, fibroblasts tend to rely more on glycolysis than oxidative phosph...

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Bibliographic Details
Main Authors: Margherita Protasoni, Jan-Willem Taanman
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/7/1002