Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology
Traumatic brain injury (TBI) is a predisposing factor for many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), Parkinson’s disease (PD), and chronic traumatic encephalopathy (CTE). Although defects in nucleocytoplasmic transport (NCT) is reported...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/67587 |