The catabolic-to-anabolic shift seen in the canine osteoarthritic cartilage treated with knee joint distraction occurs after the distraction period

The catabolic-to-anabolic shift seen in the canine osteoarthritic cartilage treated with knee joint distraction occurs after the distraction period

Background: Cartilage regenerative mechanisms initiated by knee joint distraction (KJD) remain elusive. Animal experiments that are representative for the human osteoarthritic situation and investigate the effects of KJD at consecutive time points could be helpful in this respect but are lacking. Th...

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Bibliographic Details
Main Authors: M. Teunissen, B.P. Meij, L. Snel, K. Coeleveld, J. Popov-Celeketic, I.S. Ludwig, F. Broere, F.P.J.G. Lafeber, M.A. Tryfonidou, S.C. Mastbergen
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Orthopaedic Translation
Subjects:
Canine
Knee joint distraction
Mechanical loading
Proteoglycans
TGF-β signalling
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X22000882

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http://www.sciencedirect.com/science/article/pii/S2214031X22000882

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