SARS-CoV-2 Delta Variant Displays Moderate Resistance to Neutralizing Antibodies and Spike Protein Properties of Higher Soluble ACE2 Sensitivity, Enhanced Cleavage and Fusogenic Activity

SARS-CoV-2 Delta Variant Displays Moderate Resistance to Neutralizing Antibodies and Spike Protein Properties of Higher Soluble ACE2 Sensitivity, Enhanced Cleavage and Fusogenic Activity

The SARS-CoV-2 B.1.617 lineage variants, Kappa (B.1.617.1) and Delta (B.1.617.2, AY) emerged during the second wave of infections in India, but the Delta variants have become dominant worldwide and continue to evolve. Here, we compared B.1.617 variants for neutralization resistance by convalescent s...

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Bibliographic Details
Main Authors: Sabari Nath Neerukonda, Russell Vassell, Sabrina Lusvarghi, Richard Wang, Fernando Echegaray, Lisa Bentley, Ann E. Eakin, Karl J. Erlandson, Leah C. Katzelnick, Carol D. Weiss, Wei Wang
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
SARS-CoV-2
B.1.617 variants
neutralizing antibodies
neutralization resistance
spike cleavage
syncytia formation
Online Access:https://www.mdpi.com/1999-4915/13/12/2485

Internet

https://www.mdpi.com/1999-4915/13/12/2485

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