Determining the optimal treatment target in patients with ulcerative colitis: rationale, design, protocol and interim analysis for the randomised controlled VERDICT trial

Determining the optimal treatment target in patients with ulcerative colitis: rationale, design, protocol and interim analysis for the randomised controlled VERDICT trial

Introduction Symptoms, endoscopy and histology have been proposed as therapeutic targets in ulcerative colitis (UC). Observational studies suggest that the achievement of histologic remission may be associated with a lower risk of complications, compared with the achievement of endoscopic remission...

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Main Authors: Shaji Sebastian, Silvio Danese, Séverine Vermeire, Simon Travis, Jean-Frederic Colombel, Brian G Feagan, Vipul Jairath, Guangyong Zou, Geert R D’Haens, William J Sandborn, Gordon W Moran, Christopher Ma, Peter Bossuyt, Daniel Green, Mark S Silverberg, Maria Kłopocka, Marek Horynski, Stefanie C McFarlane, Zhongya Wang, Shashi Adsul, Marcelo Freire, Gabriela Radulescu, Julie Sigler, Jurij Hanžel, Rocio Sedano, Naveen Arya, Melanie Beaton, William Harlan, Rima Petroniene, Lukasz Wolanski
Format: Article
Language:English
Published: BMJ Publishing Group 2024-07-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/11/1/e001218.full

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https://bmjopengastro.bmj.com/content/11/1/e001218.full

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