Cumulative Laxation Response with Methylnaltrexone: Implications for Hospitalized Patients with Advanced Illness and Opioid-Induced Constipation

Cumulative Laxation Response with Methylnaltrexone: Implications for Hospitalized Patients with Advanced Illness and Opioid-Induced Constipation

Background: Opioid-induced constipation (OIC) may increase the risk of fecal impaction and mortality in patients with advanced illness. Methylnaltrexone (MNTX) is efficacious for OIC. Objective: The purpose of this analysis was to evaluate cumulative rescue-free laxation response with repeat MNTX do...

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Bibliographic Details
Main Authors: David Farchadi, MD, MS, Neal E. Slatkin, MD, Nancy Stambler, DrPH, Robert J. Israel, MD, Michael Matus, MD
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Therapeutic Research
Subjects:
Analgesia
Cancer pain
Constipation
Laxatives
Methylnaltrexone
Opioid therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X23000048

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http://www.sciencedirect.com/science/article/pii/S0011393X23000048

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