Unraveling complex interplay between heat shock factor 1 and 2 splicing isoforms.

Unraveling complex interplay between heat shock factor 1 and 2 splicing isoforms.

Chaperone synthesis in response to proteotoxic stress is dependent on a family of transcription factors named heat shock factors (HSFs). The two main factors in this family, HSF1 and HSF2, are co-expressed in numerous tissues where they can interact and form heterotrimers in response to proteasome i...

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Bibliographic Details
Main Authors: Sylvain Lecomte, Léa Reverdy, Catherine Le Quément, Florent Le Masson, Axelle Amon, Pascale Le Goff, Denis Michel, Elisabeth Christians, Yves Le Dréan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3572029?pdf=render

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http://europepmc.org/articles/PMC3572029?pdf=render

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