Changes in the immune landscape of TNBC after neoadjuvant chemotherapy: correlation with relapse

Changes in the immune landscape of TNBC after neoadjuvant chemotherapy: correlation with relapse

IntroductionPatients with high-risk, triple negative breast cancer (TNBC) often receive neoadjuvant chemotherapy (NAC) alone or with immunotherapy. Various single-cell and spatially resolved techniques have demonstrated heterogeneity in the phenotype and distribution of macrophages and T cells in th...

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Bibliographic Details
Main Authors: Mohammed Ridha Moamin, Richard Allen, Steven Leslie Woods, Janet Elizabeth Brown, Harry Nunns, Anna Juncker-Jensen, Claire Elizabeth Lewis
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
triple negative breast cancer (TNBC)
multiplex optical bioassays, encoding
bioimaging and biodection
diagnostics
neoadjuvant chemotherapy (NAC)
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1291643/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1291643/full

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