Nanoscale regulation of L-type calcium channels differentiates between ischemic and dilated cardiomyopathies.

Nanoscale regulation of L-type calcium channels differentiates between ischemic and dilated cardiomyopathies.

Background: Subcellular localization and function of L-type calcium channels (LTCCs) play an important role in regulating contraction of cardiomyocytes. Understanding how this is affected by the disruption of transverse tubules during heart failure could lead to new insights into the disease. Method...

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Bibliographic Details
Main Authors: Jose L. Sanchez-Alonso, Alexandra Loucks, Sophie Schobesberger, Ankie M. van Cromvoirt, Claire Poulet, Rasheda A. Chowdhury, Natalia Trayanova, Julia Gorelik
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:EBioMedicine
Subjects:
Electrophysiology
Ion channels
Computational biology
Cardiomyopathy
Heart Failure
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420302206

Internet

http://www.sciencedirect.com/science/article/pii/S2352396420302206

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