Radiosensitization by the Selective Pan-FGFR Inhibitor LY2874455

Radiosensitization by the Selective Pan-FGFR Inhibitor LY2874455

Ionizing radiation activates cytoprotective pathways in cancer cells. Fibroblast growth factor receptor (FGFR) is a key player in these pathways. Thus, FGFR signaling is a potential target to induce radiosensitization. LY2874455 is an orally administrable selective pan-FGFR inhibitor. However, the r...

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Bibliographic Details
Main Authors: Narisa Dewi Maulany Darwis, Eisuke Horigome, Shan Li, Akiko Adachi, Takahiro Oike, Atsushi Shibata, Yuka Hirota, Tatsuya Ohno
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
cancer
radiotherapy
radiosensitization
FGFR
LY2874455
Online Access:https://www.mdpi.com/2073-4409/11/11/1727

Internet

https://www.mdpi.com/2073-4409/11/11/1727

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