Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease
<p>Abstract</p> <p>Background</p> <p>Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by cortico-striatal dysfunction and loss of glutamate uptake. At 7 weeks of age, R6/2 mice, which model an aggressive form of juvenile HD, show a...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-07-01
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Series: | Journal of Biomedical Science |
Online Access: | http://www.jbiomedsci.com/content/17/1/62 |