Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease

<p>Abstract</p> <p>Background</p> <p>Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by cortico-striatal dysfunction and loss of glutamate uptake. At 7 weeks of age, R6/2 mice, which model an aggressive form of juvenile HD, show a...

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Bibliographic Details
Main Authors: Prieto Anne L, Sari Youssef, Barton Scott J, Miller Benjamin R, Rebec George V
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/17/1/62