Estrogen as Jekyll and Hyde: regulation of cell death [v2; ref status: indexed, http://f1000r.es/4fh]

Sustained estrogenic exposure increases the risk and/or the progression of various cancers, including those of the breast, endometrium and ovary. Unexpectedly, physiological level of estrogen together with a novel IKKα inhibitor BAY11-7082 could effectively induce cell apoptosis in ER-positive breas...

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Bibliographic Details
Main Authors: Wen Zhou, Xiaoxia Zhu
Format: Article
Language:English
Published: F1000 Research Ltd 2014-09-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/3-161/v2