Neuromodulation impact on nonlinear firing behavior of a reduced model motoneuron with the active dendrite

Neuromodulatory inputs from brainstem systems modulate the normal function of spinal motoneurons by altering the activation properties of persistent inward currents (PICs) in their dendrites. However, the effect of the PIC on firing outputs also depends on its location in the dendritic tree. To inve...

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Bibliographic Details
Main Authors: Hojeong eKim, CJ eHeckman
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncom.2014.00110/full