Potential involvement of the bone marrow in experimental Graves’ disease and thyroid eye disease

Potential involvement of the bone marrow in experimental Graves’ disease and thyroid eye disease

IntroductionGraves’ disease is an autoimmune disorder caused by auto-antibodies against the thyroid stimulating hormone receptor (TSHR). Overstimulation of the TSHR induces hyperthyroidism and thyroid eye disease (TED) as the most common extra thyroidal manifestation of Graves’ disease. In TED, the...

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Bibliographic Details
Main Authors: Anne Gulbins, Mareike Horstmann, Simone Keitsch, Matthias Soddemann, Barbara Wilker, Gregory C. Wilson, Ryan Zeidan, Gary D. Hammer, Anke Daser, Nikolaos E. Bechrakis, Gina-Eva Görtz, Anja Eckstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Endocrinology
Subjects:
bone marrow
linsitinib
autoimmunity
inflammation
small molecule IGF-1R antagonist GD: Graves’ disease
thyroid eye disease (TED)
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1252727/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1252727/full

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