Novel ultrashort-acting benzodiazepine remimazolam lowers shivering threshold in rabbits

Shivering after surgery or during therapeutic hypothermia can lead to serious complications, such as myocardial infarction and respiratory failure. Although several anesthetics and opioids are shown to have anti-shivering effects, their sedative and respiratory side effects dampen the usefulness of...

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Bibliographic Details
Main Authors: Kenji Muroya, Kenta Ueda, Keiichi Wada, Masakazu Kotoda, Takashi Matsukawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1019114/full