PKHB1 peptide induces antiviral effects through induction of immunogenic cell death in herpes simplex keratitis

PKHB1 peptide induces antiviral effects through induction of immunogenic cell death in herpes simplex keratitis

Herpes simplex keratitis (HSK) is a severe, infectious corneal disease caused by herpes simplex virus type 1 (HSV-1) infection. The increasing prevalence of acyclovir resistance, the side effects of hormonal drugs, and the ease of recurrence after surgery have made it crucial to develop new methods...

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Bibliographic Details
Main Authors: Yun He, Chenchen Wang, Qi Liang, Rongjie Guo, Jiaxuan Jiang, Wenhao Shen, Kai Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
herpes simplex keratitis (HSK)
herpes simplex virus type 1 (HSV-1)
PKHB1 peptide
immunogenic cell death (ICD)
antigen-presenting cells (APCs)
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1048978/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1048978/full

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