Functional dissection of two amino acid substitutions unique to the human FOXP2 protein

Abstract The transcription factor forkhead box P2 (FOXP2) is involved in the development of language and speech in humans. Two amino acid substitutions (T303N, N325S) occurred in the human FOXP2 after the divergence from the chimpanzee lineage. It has previously been shown that when they are introdu...

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Bibliographic Details
Main Authors: Ulrich Bornschein, Hugo Zeberg, Wolfgang Enard, Wulf Hevers, Svante Pääbo
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30663-3