Alpha-mangostin inhibits viral replication and suppresses nuclear factor kappa B (NF-κB)-mediated inflammation in dengue virus infection

Alpha-mangostin inhibits viral replication and suppresses nuclear factor kappa B (NF-κB)-mediated inflammation in dengue virus infection

Abstract Severe dengue virus (DENV) infection results from viral replication and dysregulated host immune response, which trigger massive cytokine production/cytokine storm. The result is severe vascular leakage, hemorrhagic diathesis, and organ dysfunction. Subsequent to previously proposing that a...

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Bibliographic Details
Main Authors: Mayuri Tarasuk, Pucharee Songprakhon, Thaweesak Chieochansin, Kornkan Choomee, Kesara Na-Bangchang, Pa-thai Yenchitsomanus
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20284-7

Internet

https://doi.org/10.1038/s41598-022-20284-7

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