Acid sphingomyelinase/ceramide system in schizophrenia: implications for therapeutic intervention as a potential novel target

Abstract Schizophrenia is a severe mental illness, as the efficacies of current antipsychotic medications are far from satisfactory. An improved understanding of the signaling molecules involved in schizophrenia may provide novel therapeutic targets. Acid sphingomyelinase (ASM) catalyzes cellular me...

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Bibliographic Details
Main Authors: Chuanjun Zhuo, Feifei Zhao, Hongjun Tian, Jiayue Chen, Qianchen Li, Lei Yang, Jing Ping, Ranli Li, Lina Wang, Yong Xu, Ziyao Cai, Xueqin Song
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01999-7