Role of global and local topology in the regulation of gene expression in Streptococcus pneumoniae.

The most basic level of transcription regulation in Streptococcus pneumoniae is the organization of its chromosome in topological domains. In response to drugs that caused DNA-relaxation, a global transcriptional response was observed. Several chromosomal domains were identified based on the transcr...

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Bibliographic Details
Main Authors: María-José Ferrándiz, Cristina Arnanz, Antonio J Martín-Galiano, Carlos Rodríguez-Martín, Adela G de la Campa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25019515/pdf/?tool=EBI