Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.

Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.

Type 2 cytokines like IL-4 are hallmarks of helminth infection and activate macrophages to limit immunopathology and mediate helminth clearance. In addition to cytokines, nutrients and metabolites critically influence macrophage polarization. Choline is an essential nutrient known to support normal...

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Xehetasun bibliografikoak
Egile Nagusiak: Peyman Ghorbani, Sang Yong Kim, Tyler K T Smith, Lucía Minarrieta, Victoria Robert-Gostlin, Marisa K Kilgour, Maja Ilijevska, Irina Alecu, Shayne A Snider, Kaitlyn D Margison, Julia R C Nunes, Daniel Woo, Ciara Pember, Conor O'Dwyer, Julie Ouellette, Pavel Kotchetkov, Julie St-Pierre, Steffany A L Bennett, Baptiste Lacoste, Alexandre Blais, Meera G Nair, Morgan D Fullerton
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Public Library of Science (PLoS) 2023-09-01
Saila:PLoS Pathogens
Sarrera elektronikoa:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011658&type=printable

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011658&type=printable

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