Aberrant neurovascular coupling in Leber’s hereditary optic neuropathy: Evidence from a multi-model MRI analysis

Aberrant neurovascular coupling in Leber’s hereditary optic neuropathy: Evidence from a multi-model MRI analysis

The study aimed to investigate the neurovascular coupling abnormalities in Leber’s hereditary optic neuropathy (LHON) and their associations with clinical manifestations. Twenty qualified acute Leber’s hereditary optic neuropathy (A-LHON, disease duration ≤ 1 year), 29 chronic Leber’s hereditary opt...

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Bibliographic Details
Main Authors: Yi Ji, Ling Wang, Hao Ding, Qin Tian, Ke Fan, Dapeng Shi, Chunshui Yu, Wen Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Neuroscience
Subjects:
Leber’s hereditary optic neuropathy
mitochondrial disease
arterial spin labeling
regional homogeneity
neurovascular coupling
cerebral blood flow
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.1050772/full

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https://www.frontiersin.org/articles/10.3389/fnins.2022.1050772/full

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