A novel homozygous variant in PADI6 is associate with human cleavage-stage embryonic arrest

Repeated absence of useable embryos is a difficult problem for infertility patients. Among them, embryonic developmental arrest is more common, but the genetic cause is not known. The embryos of a patient who came to our hospital three times could not develop beyond the four-cell stage. In addition...

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Bibliographic Details
Main Authors: Guangyi Cao, Xiangyu Zhu, Yuling Lin, Junshun Fang, Xiaoyue Shen, Shanshan Wang, Na Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1243230/full