ER stress modulates the immune regulatory ability in gut M2 cells of patients with ulcerative colitis

Summary: This study aims to characterize the impaired immune regulatory function of Mφ obtained from UC patient colon lavage fluid (CLF). Mφs were the largest proportion (21.3 4.0%) of the CLF-derived cellular components. Less abundant and weaker immune suppressive function were observed in M2 Mφs (...

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Bibliographic Details
Main Authors: Baisui Feng, Lingzhi Xu, Shuo Song, Huazhen Liu, Yan Li, Suqin Hu, Qing Shu, Jiangqi Liu, Zhiqiang Liu, Haiqiong Yu, Pingchang Yang
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223005758