A Novel MVA-Based Multiphasic Vaccine for Prevention or Treatment of Tuberculosis Induces Broad and Multifunctional Cell-Mediated Immunity in Mice and Primates.

A Novel MVA-Based Multiphasic Vaccine for Prevention or Treatment of Tuberculosis Induces Broad and Multifunctional Cell-Mediated Immunity in Mice and Primates.

Bacille Calmette-Guérin (BCG) vaccination of new born babies can protect children against tuberculosis (TB), but fails to protect adults consistently against pulmonary TB underlying the urgent need to develop novel TB vaccines. Majority of first generation TB vaccine candidates have relied on a very...

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Bibliographic Details
Main Authors: Stéphane Leung-Theung-Long, Marie Gouanvic, Charles-Antoine Coupet, Aurélie Ray, Emmanuel Tupin, Nathalie Silvestre, Jean-Baptiste Marchand, Doris Schmitt, Chantal Hoffmann, Murielle Klein, Philip Seegren, Maria C Huaman, Anthony D Cristillo, Geneviève Inchauspé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4658014?pdf=render

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http://europepmc.org/articles/PMC4658014?pdf=render

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