Regulation of NCOA4-mediated iron recycling ameliorates paraquat-induced lung injury by inhibiting ferroptosis

Abstract Paraquat (PQ) is an irreplaceable insecticide in many countries for the advantage of fast-acting and broad-spectrum. However, PQ was classified as the most prevailing poisoning substance for suicide with no specific antidote. Therefore, it is imperative to develop more effective therapeutic...

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Bibliographic Details
Main Authors: Jing Du, Lingyan Yu, Xinyi Yang, Fangchun Shao, Jun Xia, Weidong Jin, Yinhao Zhang, Guojie Lei, Ying Wang, Yanchun Li, Jun Zhang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-024-01520-1